| Na | 135-145 |
| K | 3.5-5.0 |
| Cl | 98-107 |
| HCO₃ | 22-28 |
| Glucose | 70-110 |
| Serum Osm | 275-295 mOsm/L |
| Anion Gap | 8-12 (w/ albumin 4) |
Trinooson, C., & Patel, N. G. (2023). Fluids, electrolytes, and goal-directed therapy. In S. Elisha, J. S. Heiner, & J. J. Nagelhout (Eds.), Nurse anesthesia (7th ed., pp. 376-399). Elsevier.
Normal serum electrolytes are sodium 135 to 145 mEq/L, potassium 3.5 to 5.0 mEq/L, total calcium 9.0 to 10.5 mg/dL, magnesium 1.5 to 3.0 mEq/L, and phosphate about 2.0 to 4.7 mg/dL (Trinooson & Patel, 2023, pp. 393-398).
A preoperative potassium below 4.0 or above 5.5 mEq/L is associated with increased 30 day major adverse cardiac events, and hyperkalemia produces a predictable ECG progression from peaked T waves to a sine wave pattern and arrest above 8.5 mEq/L (Trinooson & Patel, 2023, pp. 394-395). Magnesium potentiates nondepolarizing neuromuscular blockers, so hypermagnesemic patients need careful monitoring; hypomagnesemia produces flat T waves, U waves, a prolonged QT, and arrhythmias (Trinooson & Patel, 2023, pp. 396-397).
Trinooson, C., & Patel, N. G. (2023). Fluids, electrolytes, and goal-directed therapy. In Elisha, Heiner, & Nagelhout (Eds.), Nurse anesthesia (7th ed., pp. 376-399). Elsevier.